From Traditional Analytical Chemistry to Modern Analytical Chemistry
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· Traditional Analytical Chemistry
Plainly speaking, analytical chemistry deals "Determination of substances in objective samples by chemical analysis and spectrophotometric analysis with separation/concentration".
In a variety field of analytical chemistry, "separation and concentration
of objective analyte" refers Analytical Separation, "chemical approach" refers Chemical Analysis, "spectrophotometric approach" refersSpectrophotometric Analysis, and "determination of substance" refers Quantitative analysis.
Accurate Measurements are made by such analytical approaches, and thus reliable results including quantitative results are reported. According to the analytical results, we can live healthy.
Also, trace to ultratrace analysis realizes the precise control of minor
additive, and advanced materials function.
· Modern Analytical Chemistry at Present
Based on the concept: Analytical Chemistry = Chemical Approach on Measurements, various types of analytical chemistry are developed to meet the analytical
aims.
Some research fields progressing in the field of analytical chemistry are
listed below.
- Measurements at ultra-low concentration: One molecular detection
- Chemical speciation
- From the determination of substance to the assay of activity
- Threshold analysis and simple assay
- Selective separation of substances of interest
- Observation of minute area by microscopes
- Development of analytical instruments aiming at high functionality and high sensitivity
- Comprehensive analysis including genomics and proteomics
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Point of Contact between Analytical Chemistry and Environmental Chemistry
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Understanding global environment and life systems is one of the most important matters at this modern society. How do we evaluate the global environment
and the life systems?
To understand the property of substances, it is necessary to catch the
changes in substances with their concentration, composition, and species,
as well as their transport and chemical conversion. Substances of interest
on environment often give serious influences even at their low concentrations,
and therefore, precise and accurate measurements are required.
Analytical Chemistry is such an academic area which solves the qualitative and quantitative behavior of substances
related with environment, life system, and materials through chemical measurements.
New analytical methods are sometimes necessary, and we build up the method based on the knowledge on chemistry.
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Analytical Research in Our Laboratory
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In our laboratory, "Chemical Measurement" is a research keyword. We do analytical studies in wide field of
chemistry, substances, and materials.
· Green Analytical Chemistry Directing Environment Protection
It is a serious mistake if analytical chemistry aiming at protection of environment uses such measurement systems as using harmful, hazardous and
toxic reagents.
Thus, we are aiming at developing analytical method with less environmental load and analytical methods with less consumption of energy and resources. The methodology is called as Green Analytical Chemistry. One of the example of the green analytical chemistry is to perform the chemical analysis in aquatic media without any organic solvent.
Our research is directed with "systematic approach with sophisticated chemical systems," not with new analytical reagents but with combining available reagents synergistically with the circumstance to realize the analytical goal.
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· Analysis of physicochemical properties of substances by separation
analyses
Nowadays, many types of analytical instruments are available for scientific studies.
The useful instruments may not be "black box", and they would be fully utilized by understanding their analytical principle.
We are studying novel utilization of analytical instruments including electrophoretic
and chromatographic separation for the analysis of physicochemical property of substances.
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· Development of Simple Assay and Simple Analytical Instruments
On analysing environmental or biotic samples, the first step of chemical analysis is "screening", which judges if the target sample is
"normal" or "abnormal". When any irregular matter may be suspected, detailed examination would then be made.
Screening test is conventional for the initial assay, and we study the development of simple and small instrument based on microfluidics and fluorescence detection.
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